Thursday 2 April 2009

Understanding Leukemia

The occurrence of leukemia is the production of white blood cells and excessive interference is the formation of white blood cells in the bone marrow. Cells do not develop and most of the young and immature cells that function is not clear.

Types of leukemia
Leukemia are grouped on the basis of the rapid development of this disease. Type of chronic leukemia is slow growing, while the development of acute leukemia (for a worse situation) for fast and aggressive. Besides clustering, leukemia, and depending on the type of white blood cells affected. It can be grown in myeloid cells or lymphoid cells. There are four categories of leukemia: chronic myeloid leukemia (chronic myeloid leukemia or CML), chronic leukemia lymphositic (chronic lymphocytic leukemia or CLL), acute myeloid leukemia (acute myeloid leukemia, or AML) and acute lymphoblastic leukemia (acute lymphoblastic leukemia or all).

Found that most forms of leukemia and CLL is the type of AML and CML and the nature of most species are rarely found. But in children usually is everything.

Risk of leukemia
Most of leukemia found in the age 50-60 years. But the children when they are between the ages of 2 / 4 years.

The cause of leukemia

The cause of leukemia is not fully known, but there are a number of factors to be considered the risk of leukemia. Risk factors include exposure to specific chemicals, such as chemotherapy or radiation, or some air contaminator. But most of the leukemia is not a risk factor to (cause).

Symptoms of Leukemia

Chronic leukemia no symptoms of the specific (typical), but the symptoms can be symptoms of other diseases such as pigs is not high, tired, cold sweat, stomach often not feeling well, but sometimes there and spleen enlargement. Sometimes it happens to lose appetite and body weight decreases. Usually mild symptoms (fever is not high, sweat and tired nights), which was three to six months.

But for acute leukemia, symptoms are often severe. Acute leukemia often leads to fever associated with infection. It is followed by bleeding and more severe, white blood cells, which are immature cells that cause blood vessel or groups blown stroke.



Definition of diagnosis
If you suspect that doctors leukemia, blood examination will be conducted. Because the symptoms are not specific, can be found in leukemia patients, where possible, to make "general check-up." If the estimate of the signs of leukemia cells, followed by inspections to determine whether the bone marrow biopsy. Bone marrow examination is very useful for us to check directly on white blood cells that change seems to have leukemia (difference) in the newly formed cells. If you need to do inspections will CITO genetic analysis to see whether there is mutation in cells that highlight leukemia exist.



Medicine

Medicine suspended the type of leukemia treated only symptomatic (symptom-reducing) replacing the bone marrow, often despite aggressive can cure some forms of leukemia. There is the use of drugs have focused on cell growth, which is not normal.

Treatment of acute leukemia with drug use by chemotherapy and bone marrow replacement. For CLL, some times enough to make a few remarks at this time, such as leukemia develops very slowly. But when they gradually worse, CLL, treated with chemotherapy drugs. For CML, the current standard therapy is used to the medicine called imatinib. For young patients, bone marrow transplantation is the replacement done to cure CML.


Figures for the treatment of children, can reach 75-80 percent by using new combinations of drugs, chemotherapy. The biggest problem in the treatment of leukemia is because we do not know what caused the growth of white blood cells is not normal. Meanwhile, far leukemia drug that can be routed directly to the cells that normally do not grow continually strive to study.

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